Disney villains that are female, but are of a different species. For human females, see the Women category. They are either girls or women.
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A
- Anastasia Tremaine
- Angel Lieberman
- Anglerfish
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- Ash Delgado
- Audrey (Descendants)
B
- Beatrice Le Beak
- Beatrice Stanhope
- Bebe
- Becky Moldune
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- Bella
- Belle's sisters
- Bellwether
- Bernadette the Chicken
- Bernice
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- Biana Bully
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- Birdbrain Mary
- Bizarrah
- Bizharra
- Black Fairy
- Black Heron
- Black Mariah
- Black Scorpions
- Black Widow II
- Bleak Molly
- Blind Witch
- Boston Terroriers
- Bouffant Beagle
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- Breathless Mahoney
- Brenda
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- Bride of Nine Spiders
- Bridget
- Brie
- Brie Gimmlestaub
- Brittney Wong
- Brooke
- Brooke Angels
- Brun
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- Bryn Breitbart
- Buffy and Muffy Vanderschmere
- Buffy Ratzkiwatzki
- Bugmaster
- Bunny Wiles
- Busting Candace
C
- Caldwell
- CALLIE
- Calliope
- Camille Chameleon
- Camille Leon
- Candace Adams
- Candace Montana
- Candi Brunschwegger
- Candy Cho
- Candy Sprites
- Cape Dogs
- Captain Phasma
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- Carla Delgado
- Carla Santini
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- Cassandra Bleem
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- Celestabellebethabelle
- Celia Rodriguez
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- Cerebella
- Chancellor Goodwin
- Charlene Doofenshmirtz (2nd Dimension)
- Charlotte (Jungle 2 Jungle)
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- Chatana
- Chataway Girls
- Chelsea Barnes
- Cheri
- Cherie St. Claire
- Chernabog's Ghosts, Witches and restless Soulmen
- Chief (Pucca)
- Christie Wilson
- Christina
- Christmas Star Bird
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- Circe
- Circe (DuckTales)
- CJ Hook
- Claire Miller
- Clamanda
- Clamantha
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- Cling Pow Kitties
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- Clovis
- Coach Kelly
- Coach Penny
- Cob
- Colleen Mansfield
- Comandante Camilla Reyes
- Coney Island Freaks
- Connie
- Connie Thompson
- Constance Hatchaway
- Corinne Baxter
- Cougar Mother
- Councilor Chang
- Crazy Edie
- Cruella De Vil
- Cruella De Vil (Descendants)
- Cruella De Vil (live-action)
- Cruella De Vil (Once Upon a Time)
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- Cynthia,Anthony Gamble and Stratos
D
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- Daisy Johnson (Life-Model Decoy)
- Dame Olga
- Dana Wohl
- Dance Monkey
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- Daphne
- Darci
- Dark Mother
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- Darla Shannon
- Darlene
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- Dawn Buckets
- Dawn Swatworthy
- Debbie
- Debbie Berwick
- Debbie Dazzle
- Deimata
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- Delfina
- Delia
- Delilah
- Demona
- Demonica Dixon
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- Desiree D'Allure
- Despoina
- Di Amara
- Diamondback
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- Ding and Oopo
- DNAmy
- Doga
- Dola
- Doris
- Dorothy
- Dr. Evilini
- Dr. Gevaarlijk
- Dr. Pendanski
- Dr. Quilty
- Drizella (Once Upon a Time)
- Drizella Tremaine
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- Duke and Duchess of Drear
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E
- Ebb and Flo
- Echidna
- Edna
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- Electronica
- Electronique
- Elektra
- Elena, Teresa and Yuki
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- Ellen Brandt
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- Ellen Nadeer
- Elliot, Amy, and Kurt
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- Elvira
- Ember, the Pain
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- Emily Deville
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- Emma Toldeo
- Emma Toledo
- Enfys Nest
- Erica Jones
- Erica King
- Erica Straffman
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- Esmeralda Poofenplotz
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- Estelle Dabney
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